NiHPRO® Sets a New Standard in Protein Science: Official Scientific White Paper Released

A Comprehensive Resource Backed by Over 7 Months of Research from NiHTEK’s Global Science Team

After more than seven months of rigorous scientific research, formulation refinement, and third-party testing, NiHTEK® proudly announces the release of its most comprehensive publication to date: the NiHPRO® Scientific White Paper. This groundbreaking document encapsulates the brand’s revolutionary journey in protein innovation and offers deep scientific validation for what has already become a globally disruptive product family—NiHPRO®.

The white paper, authored by Dr. Seiji Aoyagi, Chief Science Officer at NiHTEK, and co-authored by Drew Campbell (President & Co-Founder)Dr. Johan Thuvander (Chief Research Officer), and Dr. Reid Reale (Athletic Performance Director), is now available for formal request by researchers, healthcare professionals, partners, and those seeking deeper insight into the future of superior protein supplementation.

Why the NiHPRO® White Paper Matters

A First-of-Its-Kind Document in Non-Dairy Protein Innovation

Unlike typical product briefs or commercial summaries, the NiHPRO® Scientific White Paper dives deeply into the physiological, biochemical, and environmental science behind protein supplementation. It addresses:

  • Optimal protein intake across populations
  • Protein quality evaluation using gold-standard methods (DIAAS vs. PDCAAS)
  • NiHPRO’s performance in bioavailability and amino acid profile
  • Clinical potential applications, including GLP-1 receptor agonist synergy
  • Digestive tolerability, allergen-free & FODMAP certification.
  • Functional food and RTD (ready-to-drink) beverage innovation
  • Sustainability and pricing benefits over whey

This paper is not only a testament to science-backed formulation but a call to action for a new era in protein supplementation—one that centres inclusivity, digestibility, and environmental responsibility without compromising performance.

Redefining Protein Quality: DIAAS of 1.16

At the heart of the white paper lies a key data point: NiHPRO’s exceptional DIAAS score of 1.16, higher than whey protein isolate (1.09) and far above all conventional plant-based proteins. This positions NiHPRO® as a true “high-quality” protein by FAO/WHO standards.

DIAAS (Digestible Indispensable Amino Acid Score) more accurately reflects protein quality by evaluating ileal amino acid absorption, a method endorsed by global nutrition authorities. The evaluation for NiHPRO® was conducted using the internationally recognized INFOGEST in vitro model by CIAL (Institute of Food Science Research) in Spain—a gold standard in ethical, reproducible protein testing.

Amino Acid Superiority: Especially Arginine and Leucine

The white paper devotes multiple pages to NiHPRO’s exceptional amino acid profile, particularly its naturally high levels of arginine (8g/100g) and leucine (10g/100g).

  • Leucine: Key driver of muscle protein synthesis (MPS)through the mTORC1 pathway. Vital for aging populations and GLP-1 users.
  • Arginine: Enhances nitric oxide (NO)production, blood flow, collagen synthesis, growth hormone release, and GLP-1 secretion.

NiHPRO® contains nearly 4x more arginine than whey protein isolate. This makes it not only an elite sports protein but also a strong candidate for clinical nutrition, trauma recovery, and metabolic health.

Protein for EveryBODY™: Allergen-Free, Digestive-Friendly, and Certified FODMAP-Free

No Soy. No Gluten. No Lactose. No Bloating.

What truly sets NiHPRO® apart is its universal digestibility.

Further strengthening its inclusive profile, NiHPRO® is the world’s first 100% FODMAP-free protein isolate, certified by the FODMAP Friendly Certification Program (Australia). This makes it uniquely suitable for individuals with:

  • IBS (Irritable Bowel Syndrome)
  • GLP-1-related digestive issues
  • General GI sensitivity

Consumers now have access to a protein that is as gentle on the gut as it is effective for performance and recovery.

NiHPRO® and GLP-1 Users: A New Nutritional Companion

With the rise of GLP-1 receptor agonists, such as semaglutide and tirzepatide, maintaining muscle mass while losing fat has become increasingly complex. NiHPRO® directly supports this need:

  • High protein density in small servings
  • Leucine-rich for lean mass retention
  • Sugar-free and low-GI to stabilize insulin response
  • Partially hydrolysed for fast gastric emptying

Patent-Pending Innovation: APH™ and MPi™ Technology

NiHPRO® is not simply a blend of ingredients—it is the result of two patent-pending technologies:

1. Advanced Precision Hydrolysis™ (APH™)

  • Optimizes bioavailability and digestibility
  • Mimics early digestive breakdown to enhance absorption

2. Molecular Protein Infusion™ (MPi™)

  • Improves taste, solubility, and texture
  • Makes NiHPRO® virtually indistinguishable from dairy protein for most consumers

These innovations overcome the traditional bitterness, grittiness, or flat flavours found in plant-based or hydrolysed proteins.

Introducing the NiHPRO®Family: Powders, Beverages, and Snacks

The release of the white paper coincides with NiHTEK’s strategic expansion of the NiHPRO®Family, creating a full-circle solution for functional food brands, athletes, healthcare providers, and consumers.

1. NiHPRO®Core

The original disruptor—now launched as NiHPRO®Core 2.0 with:

  • Reduced sodium
  • Cleaner taste and mouthfeel
  • Enhanced formulation flexibility
  • Still DIAAS 1.16+

2. NiHPRO®Bev

A next-generation isolate developed specifically for RTD (Ready-to-Drink) applications.

Key features:

  • No sedimentation or separation
  • FODMAP-free, stable under UHT
  • Retains full nutritional value (Leu, Arg, EAA)
  • Ideal for protein drinks, medical beverages, and shakes

3. NiHPRO®Puffs (Launching August 2025)

A game-changing protein format for snacks, cereals, and crisp-based applications.

Attributes include:

  • Light, crunchy texture
  • 55%+ protein content
  • Excellent puff expansion
  • No soy, no binders, no bitterness
  • Low carbohydrate

Looking Ahead: Research, Certification, and Clinical Use

In addition to the white paper’s current findings, NiHTEK is pursuing:

  • Informed Protein®certification for label transparency and amino acid integrity
  • Informed Choice®anti-doping validation for athlete safety
  • Future clinical research on metabolic health, aging, and recovery protocols
  • Ongoing global regulatory expansion

With safety, efficacy, and compliance at its core, NiHPRO® is set to redefine not only sports and lifestyle nutrition but also clinical protein interventions worldwide.

Conclusion: A Turning Point for Inclusive, Science-Driven Protein

The release of the NiHPRO® Scientific White Paper is a landmark moment in the evolution of protein science.

More than just a summary of what NiHTEK® has achieved, it is a blueprint for the future, where science, performance, inclusivity, and sustainability are non-negotiable standards. With the launch of the NiHPRO®Family—Core, Bev, and Puffs, NiHTEK® delivers the first complete, high-performance protein solution for every format, every function, and Protein For EveryBODY™.

Request a Copy

The NiHPRO® Scientific White Paper is available to:

  • Industry professionals and partners
  • Sports and medical practitioners
  • Ingredient formulators
  • Dietitians and nutritionists
  • Media and research journalists

📩 To request your formal copy, please contact: info@nihtek.com or visit www.nihtek.com

NiHPRO® — Protein For EveryBODY™. Now clinically proven. Scientifically validated. Sensory perfected.

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